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    PaSER - Parallel database Search Engine in Real-time

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    Traditionally data acquisition has been the bottleneck for large scale proteomics. This has also remained one of the limitations in leveraging mass spectrometry within the clinic.

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    What Is Radiotherapy?

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    Whilst the development of radiotherapy began as early as 1900 – with Marie and Pierre Curie suggesting X-rays could be used to treat tumors – radiotherapy, as we know it, wasn’t conceived until the 1920s. In this article, we take a closer look at how radiotherapy is used to treat cancer.

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    The Culture of Cell Culturing: Be Careful Not To Contaminate!

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    Researchers must consider a number of factors for in vitro experiments. Selecting the most appropriate cell line or primary culture for the project at hand is only the first step. Researchers must then be vigilant to prevent contaminating the culture, from the initial moments it is plated and all throughout consecutive passages.

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    Blueprints for a Revolutionary Single-Molecule Microscope Published
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    A team from the University of Sheffield has designed and built a specialist microscope and shared the build instructions to help make this equipment available worldwide.

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    Antidepressant Halts Growth of Childhood Sarcoma in Animal and Cell-Based Studies
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    Blood Cell Mutations Confound Prostate Cancer Liquid Biopsy
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    Unrelated mutations, when present in the blood, can lead to false positive results in men with advanced prostate cancer who are undergoing liquid biopsies.

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    Proteomics Study Profiles Protein Changes in Response to Anticancer Drugs
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    Researchers have generated a resource to aid in predicting drug sensitivity, to understand therapeutic resistance mechanisms, and identify optimal combination treatment strategies.

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    Exposing the Origin of Neuroblastoma To Guide Treatment
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    New research shows that bilateral neuroblastoma cancers can arise independently from each other, rather than having metastasized from one site to another. This finding has important implications for understanding the origins of neuroblastoma and could help the development of more efficacious treatments.

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    Exploring Ways To Boost Immunotherapy Success for Stomach Cancer
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    Immunotherapy for stomach cancer may work better if it is administered to the patient sooner, in the earlier stages of disease, and in combination with standard chemotherapy, a new study suggests.

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    The Coronavirus Pandemic
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    On December 31, 2019, the first cases of a novel coronavirus were identified in Wuhan City, Hubei Province, China. Here, we curate a collection of news and content related to what has become the COVID-19 pandemic.

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    Repurposing and Combining Drugs – An Effective Cancer Treatment Strategy
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    Dr Robert Nagourney is having success investigating whether a unique combination of existing and approved cancer drugs might be more effective compared to “off-the-shelf” treatments. Technology Networks recently had the pleasure of speaking with Nagourney to learn more about his work focused on repurposing drugs. He discusses the challenges and benefits of exploring new uses for drugs that are outside the scope of their original indication.

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    Personalized Medicine Model Aiming To Improve Diagnosis and Treatment of Chronic Diseases
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    To learn more about the PANDIS model, its aims, and how it can be used to help diagnose and treat patients suffering from a range of conditions spanning from cancers to “mystery chronic diseases”, Technology Networks spoke with PANDIS’s founders, Professor Gilles Guillemin and Catherine Stace.

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    What's the Physiological Relevance? A Profile of Oded Rechavi
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    A profile piece exploring the life and career of the molecular biologist Professor Oded Rechavi.

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    Recent Advances and Applications of Single-Cell Sequencing
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    Here, we review the most commonly adopted technologies and workflows available for single-cell sequencing and discuss current research studies adopting such approaches.

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    Avoiding a Cancer Care Crisis During the COVID-19 Pandemic
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    The medical profession had to think on its feet responding to the demands of the pandemic. But, in doing so, every medical discipline from general practice to palliative care has taken a hit. Of particular concern is how delays to screening, diagnosis and treatment of cancer have already impacted morbidity and mortality rates, with cancer death rates looking likely to rise significantly over the coming years.

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